Package: scINSIGHT
Type: Package
Title: Interpretation of Heterogeneous Single-Cell Gene Expression Data
Version: 0.1.4
Date: 2022-05-29
Authors@R: c(person(given = "Kun", family = "Qian", role = c("aut","ctb","cre"), email = "Kun_Qian@foxmail.com", comment = c(ORCID = "0000-0002-2354-2238")),
             person(given = "Wei Vivian", family = "Li", role = c("aut","ctb"), email = "vivian.li@rutgers.edu", comment = c(ORCID = "0000-0002-2087-2709")))
Maintainer: Kun Qian <Kun_Qian@foxmail.com>
Description: We develop a novel matrix factorization tool named
        'scINSIGHT' to jointly analyze multiple single-cell gene
        expression samples from biologically heterogeneous sources,
        such as different disease phases, treatment groups, or
        developmental stages. Given multiple gene expression samples
        from different biological conditions, 'scINSIGHT'
        simultaneously identifies common and condition-specific gene
        modules and quantify their expression levels in each sample in
        a lower-dimensional space. With the factorized results, the
        inferred expression levels and memberships of common gene
        modules can be used to cluster cells and detect cell
        identities, and the condition-specific gene modules can help
        compare functional differences in transcriptomes from distinct
        conditions. Please also see Qian K, Fu SW, Li HW, Li WV (2022)
        <doi:10.1186/s13059-022-02649-3>.
License: GPL-3
Imports: Rcpp, RANN, igraph, parallel, stats, stringr
LinkingTo: Rcpp, RcppArmadillo
Depends: methods
URL: https://github.com/Vivianstats/scINSIGHT,
        https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02649-3
NeedsCompilation: yes
Packaged: 2026-10-11 10:51:55 UTC; root
Author: Kun Qian [aut, ctb, cre]
        (<https://orcid.org/0000-0002-2354-2238>), Wei Vivian Li [aut,
        ctb] (<https://orcid.org/0000-0002-2087-2709>)
Config/pak/sysreqs: libglpk-dev libicu-dev libxml2-dev
Repository: https://vivianstats.r-universe.dev
Date/Publication: 2022-05-29 06:35:19 UTC
RemoteUrl: https://github.com/vivianstats/scinsight
RemoteRef: HEAD
RemoteSha: 8f20e61b6a5a3419d849b1c84e48b13457598c04